Treatment of Chronic Discoid Lupus Erythematosus with Topical Tacrolimus

Chronic cutaneous (discoid) lupus erythematosus.

Four cases of facial discoid lupus erythematosus successfully treated with topical pimecrolimus or tacrolimus.

Discoid lupus erythematosus (DLE), which is a cutaneous form of lupus erythematosus (LE), is generally refractory to a wide range of topical or systemic therapies. Although the main treatment option for DLE is topical steroids, it is often ineffective or likely to produce long-term side effects. New drugs, including tacrolimus and pimecrolimus, have been developed to overcome the adverse effect...

Successful treatment of discoid lupus erythematosus with argon laser.

Vascular lesions with telangiectasias on visible areas, such as the face, are common in discoid lupus erythematosus (DLE); however, an efficient management of these skin lesions can sometimes be difficult. Since argon laser light is able to specifically coagulate vascular structures, it has been used in the treatment of various vascular skin malformations. Therefore, we addressed the issue whet...

Successful treatment of recalcitrant discoid lupus erythematosus with ustekinumab.

We report a 52-year old woman with a 28-year historyof disfiguring facial discoid lupus erythematosus(DLE), persistent despite both classical therapiesand rituximab. Ustekinumab 45 mg was started incombination with methotrexate and intralesionalcorticosteroids. Methotrexate and intralesionalcorticosteroids were withdrawn 30 months later andustekinumab maintained as monotherapy. Fortyeight month...

Successful treatment of discoid lupus erythematosus with chloroquine.

Successful Treatment of Discoid Lupus Erythematosus with Chloroquine Laurentius A. Pramono, Resultanti, Suryo Anggoro, Sandra Langow, Rudy Hidayat, Bambang Setyohadi, Harry Isbagio Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Correspondence mail: Department of Internal Medicine, Faculty of Medicine University of I...